PRENATAL DIAGNOSIS DUOFERTILITY TEST or COMBINED TEST (TWIN DNA TEST)
WHAT IS THE TWIN DNA TEST?
It’s a blood test in which two molecules in the mother’s blood are measured during pregnancy: ß-hCG and PAPP-A.
WHAT IS THE COMBINED TEST?
It’s the association of Twin DNA Test and genetic sonography in the first quarter, with a measurement of nuchal translucency (NT), to determine the risk that the fetus could be affected by a chromosomal abnormality, specifically Trisomy 21 (Downs Syndrome), trisomy 13 and trisomy 18 with a sensitivity of over 90%.
HOW DO YOU INTERPRET THE RESULTS OF THE COMBINED TEST?
In the report the patient will find a numeric result expressed as a probability index. The test is considered negative when the risk is greater than 1:350 (example 1: 5429. If the estimated risk is less than 1:350 (i.e. 1:146), the patient will have the right to be subjected to invasive diagnostic procedures, chorionic villus sampling or amniocentesis, if deemed appropriate.
WHAT ARE THE LIMITS OF THE COMBINED TEST?
The Combined Test is an examination of probability and does not permit you to recognize or exclude a chromosomal abnormality ith absolute certainty. If the risk is high, the fetus can be healthy, if the risk is low, the fetus may also be affected. The test works especially for some anomalies and chromosomal abnormalities, such as trisomy 21, 13, 18 and monosomy X. There are other more severe chromosomal abnormalities and rarer occurrence, which are not detectable by the combined test.
WHICH PATIENT IS THE BEST CANDIDATE FOR THE COMBINED TEST?
They could perform a free Combined Test on the patients who have not yet reached age 35 by the date of their child’s birth. Patients over age 35, or who will turn 35 by the date of their child’s birth, can still take the test, but under the care of a private physician.
AFTER HOW MANY DAYS DO THE RESULTS COME IN?
The test results are obtained in about 7 days. All responses are reviewed by the doctors in charge of the service. The patient is contacted personally in case of alterations of the test, alternatively, the results will be mailed to her home.
ARE THERE ANY RISKS INVOLED FOR PATIENTS WHO HAVE THIS TEST DONE?
The Combined Test does not increase the risk of miscarriage.